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+7
06 November 2025

Protein FSP1 found to help melanoma survive in lymph nodes

New research has discovered a key survival mechanism in metastatic melanoma, revealing that cancer cells spreading to lymph nodes depend on a protein called FSP1 to avoid cell death....

Drug Target Review Drug Target Review
November 6, 2025 1 min read
Animal Models
Drug Development
Drug Discovery Processes
Immuno-oncology
Immunotherapy
Monoclonal Antibody
Oncology
Translational Science
+7
06 November 2025

Sugar-coated tumours: a new target for pancreatic cancer

Researchers have discovered that pancreatic tumours evade the immune system by disguising themselves with a sugar coating. To combat this, they have developed a new antibody therapy that blocks this ‘...

Drug Target Review Drug Target Review
November 6, 2025 1 min read
Drug Discovery
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Ion Channels
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+6
04 November 2025

Meet WRPRFa: the precision peptide changing how we study pain

A newly developed peptide, WRPRFa, is giving scientists a clearer view of how the acid-sensing ion channel (ASIC3) drives pain signalling. ...

Drug Target Review Drug Target Review
November 4, 2025 1 min read
Drug Discovery
Drug Discovery Processes
Ion Channels
Neurosciences
Peptide Therapeutics
Pharmacology
Target Validation
+6
04 November 2025

Meet WRPRFa: the precision peptide changing how we study pain

A newly developed peptide, WRPRFa, is giving scientists a clearer view of how the acid-sensing ion channel (ASIC3) drives pain signalling. ...

Drug Target Review Drug Target Review
04 November 2025 1 min read
Artificial Intelligence
Disease Research
Drug Discovery
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Genomics
Molecular Biology
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+7
24 October 2025

The predictive validity crisis: Pharma’s productivity paradox – Part II

Part II shows that the predictive validity crisis can be solved by rethinking how the industry chooses models, measures outcomes and integrates systems. Success stories from Vertex, Regeneron and Astr...

Carrie Haslam Carrie Haslam
24 October 2025 1 min read
Analysis
Assays
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Gene Therapy
Genetic Analysis
Lipidomics
Lipids
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+8
17 October 2025

SPNS1 mutations reveal new lysosomal lipid recycling pathway

Scientists have linked rare mutations in SPNS1 to a previously unknown lipid recycling pathway in lysosomes, revealing how faulty fat processing can trigger muscle and liver disease....

Carrie Haslam Carrie Haslam
17 October 2025 1 min read
Research and Development
25 August 2025

Final Webinar – Levon – August 2025

Explore how a Weight of Evidence (WoE) approach uses in vitro methods and artificial intelligence (AI) to transform carcinogenicity risk assessment, reducing reliance on animal studies while enhancing...

Carrie Haslam Carrie Haslam
25 August 2025 1 min read
Drugs and Therapies
In Vitro
Research and Development
Technology
Tools & Techniques
Tools and techniques
Translational Science
+6
12 August 2025

Overcoming Affinity and Expression Bottlenecks in TCR Discovery

Join this expert-led webinar to learn how to break through common bottlenecks in TCR discovery with practical strategies that help teams move faster and smarter....

Carrie Haslam Carrie Haslam
12 August 2025 1 min read
Antibodies
Cell Cultures
Cell Line Development
Drugs & Therapies
Drugs and Therapies
Gene Therapy
In Vitro
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+9
29 July 2025

Innovating Obesity Drug Discovery: Trends, Challenges, and Translational Strategies

Facing roadblocks in obesity drug discovery? Discover how integrated, validated strategies are helping teams accelerate development and reduce risk....

Carrie Haslam Carrie Haslam
29 July 2025 1 min read
Animal Models
Drug Development
Drug Discovery Processes
Immuno-oncology
Immunotherapy
Monoclonal Antibody
Oncology
Translational Science
+7
06 November 2025

Sugar-coated tumours: a new target for pancreatic cancer

Researchers have discovered that pancreatic tumours evade the immune system by disguising themselves with a sugar coating. To combat this, they have developed a new antibody therapy that blocks this ‘...

Drug Target Review Drug Target Review
06 November 2025 1 min read
Analysis
Computational techniques
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Molecular Biology
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+6
06 November 2025

RNA folding: new model could change future drug design

A Japanese research team has simulated how RNA molecules fold, using cutting-edge computational tools to model complex structures with accuracy – a breakthrough that could accelerate the development o...

Drug Target Review Drug Target Review
06 November 2025 1 min read
Central Nervous System (CNS)
Drug Targets
Enzymes
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+7
06 November 2025

BVRA enzyme may slow down Alzheimer’s progression

New research from Johns Hopkins Medicine reveals that the enzyme BVRA protects brain cells from oxidative stress, allowing for potential new methods for treating neurodegenerative diseases like Alzhei...

Drug Target Review Drug Target Review
06 November 2025 1 min read
Drugs and Therapies
23 July 2025

Beyond the Lab: Stem cell research – TEST

Our latest 'Beyond the Lab' report explores cutting-edge advancements in stem cell research, highlighting their potential to revolutionise treatments for chronic diseases and cancer, and advance regen...

Carrie Haslam Carrie Haslam
23 July 2025 1 min read
Drugs and Therapies
13 February 2025

Beyond the Lab: Stem cell research

Our latest 'Beyond the Lab' report explores cutting-edge advancements in stem cell research, highlighting their potential to revolutionise treatments for chronic diseases and cancer, and advance regen...

Carrie Haslam Carrie Haslam
13 February 2025 1 min read
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Drugs and Therapies
30 January 2025

Drug Target Review – Issue 4 2023

A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening. ...

Carrie Haslam Carrie Haslam
30 January 2025 1 min read
Technology
Tools and techniques
+1
22 February 2024

Video: Dianthus for identifying Microcycle® hits

Hear how Dr. Reece Gardner from Curve Therapeutics uses the Dianthus instrument with Spectral Shift technology to validate Microcycle® hits....

Carrie Haslam Carrie Haslam
22 February 2024 1 min read
Clinical Trials
Drugs and Therapies
Machine learning
Research and Development
Tools and techniques
+4
05 August 2025

Beyond the Lab: Biomarkers Powering Tomorrow’s Therapies

Biomarkers are redefining how precision therapies are discovered, validated and delivered. This exclusive expert-led report reveals how leading teams are using biomarker science to drive faster insigh...

Carrie Haslam Carrie Haslam
05 August 2025 1 min read
Cell Line Development
Clinical Trials
Drugs & Therapies
Drugs and Therapies
Gene Therapy
Research and Development
+5
07 July 2025

Transform your drug discovery pipeline with 3D cellular models

Expert insights reveal how 3D cellular models are revolutionising preclinical testing and clinical translation....

Carrie Haslam Carrie Haslam
07 July 2025 1 min read
CRISPR
Drugs and Therapies
Genomics
Research and Development
Tools & Techniques
Tools and techniques
+5
08 May 2025

App Note: High-Throughput Single-Cell Genome Profiling

See how the new Shasta™ Single Cell System enabled high-throughput single-cell DNA-seq library preparation to detect tumor-driving mutations....

Carrie Haslam Carrie Haslam
08 May 2025 1 min read

News

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Animal Models
Cancer research
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In Vivo
Oncology
Therapeutics
Translational Science
+7
06 November 2025

Protein FSP1 found to help melanoma survive in lymph nodes

New research has discovered a key survival mechanism in metastatic melanoma, revealing that cancer cells spreading to lymph nodes depend on a protein called FSP1 to avoid cell death....

Drug Target Review Drug Target Review
November 6, 2025 • 1 min read
Animal Models
Drug Development
Drug Discovery Processes
Immuno-oncology
Immunotherapy
Monoclonal Antibody
Oncology
Translational Science
+7
06 November 2025

Sugar-coated tumours: a new target for pancreatic cancer

Researchers have discovered that pancreatic tumours evade the immune system by disguising themselves with a sugar coating. To combat this, they have developed a new antibody therapy that blocks this ‘...

Drug Target Review Drug Target Review
November 6, 2025 • 1 min read
Analysis
Computational techniques
Drug Discovery
Drug Discovery Processes
Molecular Biology
Structural Biology
Translational Science
+6
06 November 2025

RNA folding: new model could change future drug design

A Japanese research team has simulated how RNA molecules fold, using cutting-edge computational tools to model complex structures with accuracy – a breakthrough that could accelerate the development o...

Drug Target Review Drug Target Review
November 6, 2025 • 1 min read
Central Nervous System (CNS)
Drug Targets
Enzymes
Mitochondria
Neuroprotection
Neurosciences
Pharmacology
Translational Science
+7
06 November 2025

BVRA enzyme may slow down Alzheimer’s progression

New research from Johns Hopkins Medicine reveals that the enzyme BVRA protects brain cells from oxidative stress, allowing for potential new methods for treating neurodegenerative diseases like Alzhei...

Drug Target Review Drug Target Review
November 6, 2025 • 1 min read
Cell Cultures
Disease Research
Hepatocytes
In Vitro
Induced Pluripotent Stem Cells (iPSCs)
Organoids
Regenerative Medicine
Translational Science
+7
04 November 2025

Lab-grown liver offers new platform to test fibrosis drugs

Japanese scientists have developed a lab-grown liver organoid that mimics human liver regeneration, offering a new platform to study fibrosis and test therapies. ...

Drug Target Review Drug Target Review
November 4, 2025 • 1 min read

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Drugs and Therapies

Levon – Test – Aug 2025

Our latest 'Beyond the Lab' report explores cutting-edge advancements in stem cell research, highlighting their potential to revolutionise treatments for chronic diseases and cance...

Carrie Haslam Carrie Haslam
August 11, 2025 1 min read
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Drugs and Therapies

Beyond the Lab: Stem cell research – TEST

Our latest 'Beyond the Lab' report explores cutting-edge advancements in stem cell research, highlighting their potential to revolutionise treatments for chronic diseases and cance...

Carrie Haslam Carrie Haslam
July 23, 2025 1 min read
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Drugs and Therapies

Beyond the Lab: Stem cell research

Our latest 'Beyond the Lab' report explores cutting-edge advancements in stem cell research, highlighting their potential to revolutionise treatments for chronic diseases and cance...

Carrie Haslam Carrie Haslam
February 13, 2025 1 min read
Drugs and Therapies

Drug Target Review – Issue 4 2023

A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening. ...

Carrie Haslam Carrie Haslam
January 30, 2025 1 min read
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Beyond the lab: antibodies

Amidst a new wave of innovation in antibody research, this report highlights recent breakthroughs across fields such as cancer research and neuroscience, showcasing how advancement...

Carrie Haslam Carrie Haslam
October 24, 2024 1 min read

Webinars

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Research and Development
Carrie Haslam Carrie Haslam
October 15, 2025 • 1 Minute

Final Webinar – Levon – August 2025

Explore how a Weight of Evidence (WoE) approach uses in vitro methods and artificial intelligence (AI) to transform carcinogenicity risk assessment, r...

Drugs and Therapies
In Vitro
Research and Development
Technology
Tools & Techniques
Tools and techniques
Translational Science
+6
Carrie Haslam Carrie Haslam
August 12, 2025 • 1 Minute

Overcoming Affinity and Expression Bottlenecks in TCR Discovery

Join this expert-led webinar to learn how to break through common bottlenecks in TCR discovery with practical strategies that help teams move faster a...

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Featured Whitepapers

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Clinical Trials
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+4
05 August 2025

Beyond the Lab: Biomarkers Powering Tomorrow’s Therapies

Biomarkers are redefining how precision therapies are discovered, validated and delivered. This exclusive expert-led report reveals how leading teams ...

Carrie Haslam Carrie Haslam
Aug 5, 2025 • 1 min read
Cell Line Development
Clinical Trials
Drugs & Therapies
Drugs and Therapies
Gene Therapy
Research and Development
+5
07 July 2025

Transform your drug discovery pipeline with 3D cellular models

Expert insights reveal how 3D cellular models are revolutionising preclinical testing and clinical translation....

Carrie Haslam Carrie Haslam
Jul 7, 2025 • 1 min read
CRISPR
Drugs and Therapies
Genomics
Research and Development
Tools & Techniques
Tools and techniques
+5
08 May 2025

App Note: High-Throughput Single-Cell Genome Profiling

See how the new Shasta™ Single Cell System enabled high-throughput single-cell DNA-seq library preparation to detect tumor-driving mutations....

Carrie Haslam Carrie Haslam
May 8, 2025 • 1 min read
Clinical Trials
Research and Development
Technology
+2
29 April 2025

Beyond the Lab: Clinical Trials

Explore how artificial intelligence (AI), biomarkers, and innovative trial technologies are creating a more efficient, data-driven future for drug dis...

Carrie Haslam Carrie Haslam
Apr 29, 2025 • 1 min read
Covid-19
CRISPR
Drugs & Therapies
Drugs and Therapies
Gene Therapy
RNAs
T cells
+6
22 April 2025

Guide: Create DNA Template for In Vitro mRNA Synthesis

Learn how to simplify the entire DNA template generation workflow, streamlining mRNA therapeutic research....

Carrie Haslam Carrie Haslam
Apr 22, 2025 • 1 min read
Cell Line Development
Chimeric Antigen Receptors (CARs)
Drugs & Therapies
Drugs and Therapies
Gene Therapy
Research and Development
+5
07 April 2025

Poster: Lentiviral Gene Delivery Workflow

Use this lentiviral gene delivery workflow poster to understand how to optimize your workflow for successful viral transduction....

Carrie Haslam Carrie Haslam
Apr 7, 2025 • 1 min read
Drugs and Therapies
Machine learning
Technology
Tools and techniques
+3
21 March 2025

Beyond the Lab: Artificial Intelligence

Download our latest report to discover how AI is transforming drug discovery, accelerating treatments and driving personalised care....

Carrie Haslam Carrie Haslam
Mar 21, 2025 • 1 min read

Featured Videos

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12 August 2025

Video – August 2025 – Levon

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Fusce vitae est fermentum, pulvinar sem in, convallis ligula. Proin sodales tortor non ipsum ...

Carrie Haslam Carrie Haslam
Aug 12, 2025 • 1 min read
Technology
Tools and techniques
+1
22 February 2024

Video: Dianthus for identifying Microcycle® hits

Hear how Dr. Reece Gardner from Curve Therapeutics uses the Dianthus instrument with Spectral Shift technology to validate Microcycle® hits....

Carrie Haslam Carrie Haslam
Feb 22, 2024 • 1 min read
Drugs and Therapies
Genomics
Research and Development
Technology
Tools and techniques
+4
02 March 2023

Video: Spatial imaging as a tool for discovery

Watch Dr David Rimm from the Yale School of Medicine talk about his recent work and take on the future of multiplex spatial profiling of the TME....

Carrie Haslam Carrie Haslam
Mar 2, 2023 • 1 min read
Drugs and Therapies
Genomics
Research and Development
Technology
Tools and techniques
+4
24 November 2022

Video: Proteomics solutions for drug discovery

Dr. Stokes, Associate Director Proteomics, discusses how proteomic studies can increase effectiveness, speed of target and biomarker identification....

Carrie Haslam Carrie Haslam
Nov 24, 2022 • 1 min read
Drugs and Therapies
Research and Development
+1
26 September 2022

Video: Keep your samples safe – disinfect with UV light

The pipetting robot, flowbot® ONE, is available with UV light to make clean-up processes easy and effective, enabling you to keep your samples safe....

Carrie Haslam Carrie Haslam
Sep 26, 2022 • 1 min read