Drug Target Review – Issue 2 2022

In this issue are articles focusing on a novel stem cell therapy for hearing loss, how a non-linear chiroptical effect could aid drug discovery and the advantages of cryo-electron tomography for imaging research. Also included are pieces on gene therapy, spheroids and genomics. 

Included in this issue:

• SCREENING
  Miniaturising organoid drug screens using nanofibrillar cellulose hydrogels
  Dr Tijmen Booij and Dr Christian Stirnimann, ETH Zurich
• BIOANALYSIS
  A multi-step analysis including GCI reveals novel insight into LPS translocation
  Dr Michael Hennig, leadXpro
• IMAGING
  The bigger picture: innovation in microscopy
  Dr Peter O’Toole, University of York
• CELL & GENE THERAPY
  Providing new hope for rare disease using non-viral gene therapy
  Brent Warner, Poseida Therapeutics
• ANTIBODIES
  Antibody pipelines – the pharma perspective
  Dr Erik Vernet, Novo Nordisk
• GENOMICS 
  Whole genome sequencing in cancer research
  Dr Andrea Degasperi, University of Cambridge
• STEM CELLS
  New immune targets to improve survival from sepsis
  Daniel Morales-Mantilla, Dr Robin Parihar and Dr Katherine King, Baylor College of Medicine