Video: Using luciferase reporter cell lines for HTS readouts

This video reviews the uses and advantages of reporter cell lines in the context of cellular research and drug discovery.

Reporter cell lines are critical tools that serve as models for tissue types or disease states, engineered to express a reporter protein, such as luciferase, upon exogenous stimulation. Using reporter cell lines provides a convenient and simple readout to screen for inhibitors of protein signaling or activation. This video reviews the uses and advantages of reporter cell lines in the context of cellular research.