Whitepaper

MEA to probe ALS phenotypes in neuronal disease models

Carrie Haslam

6 Feb 2024 0 min read

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Carrie Haslam
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Early-stage ALS drug discovery workflows can be challenging due to a lack of access to consistent, physiologically relevant human cell models. In this app note, discover a functional iPSC-derived neuronal model of ALS from bit.bio. Also, explore an MEA workflow featuring the Axion Maestro Pro that was used to validate this model’s reduced neuronal activity and network formation compared to a genetically matched control, highlighting its physiological relevance for pre-clinical ALS research.

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MEA to probe ALS phenotypes in neuronal disease models

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